Gonadotropin-releasing hormone agonists for ovarian protection during cancer chemotherapy: systematic review and meta-analysis.

J C SenraMatheus RoqueM C T TalimFernando Marcos Dos ReisR L C Tavares

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2017)

Evidence, albeit of low quality, supports the use of GnRHa before and/or during chemotherapy to reduce the risk of POI and increase the probability of spontaneous pregnancy in the short term. Further high quality RCTs with more accurate assessment of ovarian reserve are needed to support definitive recommendations for clinical practice. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

clinical practice
locally advanced
papillary thyroid
rectal cancer
squamous cell carcinoma
squamous cell
high resolution
pregnant women
quality improvement
pregnancy outcomes
systematic review
lymph node metastasis
young adults