Germline mutations of homologous recombination genes and clinical outcomes in pancreatic cancer: a multicenter study in Taiwan.

Siao Muk ChengYung-Yeh SuNai-Jung ChiangChih-Jung WangYing-Jui ChaoChien-Jui HuangHui-Jen TsaiShang-Hung ChenChi-Yen ChangChia-Rung TsaiYi-Jie LiChia-Jui YenShih-Chang ChuangJeffrey Shu-Ming ChangYan-Shen Shan Daw-Yang Hwang Li-Tzong Chen

Published in: Journal of biomedical science (2024)

patients treated with 1L platinum-based chemotherapy highlights the importance of germline testing for all patients with advanced PDAC at diagnosis.

Keyphrases

dna repair
dna damage
genome wide
locally advanced
bioinformatics analysis
genome wide identification
oxidative stress
squamous cell carcinoma
gene expression
radiation therapy