Embedding electronic health records onto a knowledge network recognizes prodromal features of multiple sclerosis and predicts diagnosis.
Charlotte A NelsonRiley M BoveAtul J ButteSergio E BaranziniPublished in: Journal of the American Medical Informatics Association : JAMIA (2022)
Using data from EHR as input, SPOKEsigs describe patients at both the clinical and biological levels. We provide a clinical use case for detecting MS up to 5 years prior to their documented diagnosis in the clinic and illustrate the biological features that distinguish the prodromal MS state.