In vivo cerebral metabolic and dopaminergic characteristics in multiple system atrophy with orthostatic hypotension.
Chenxi XueXiaofeng DouCongcong YuYan ZhongJing WangXiang ZhangLe XueDaoyan HuShuang WuHong ZhangMei TianPublished in: European journal of nuclear medicine and molecular imaging (2023)
In this study, the changes in glucose metabolism in the pons, right cerebellar tonsil, left parahippocampal gyrus and left superior temporal gyrus were found closely related to OH in MSA patients. And the decreased presynaptic dopaminergic function in the left caudate may contribute to OH in MSA. Taken together, this study provided in vivo pathophysiologic information on MSA with OH from neuroimaging approach, which is essential for a better understanding of MSA with OH.