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Efficacy and safety of talazoparib in Japanese patients with germline BRCA-mutated locally advanced or metastatic breast cancer: results of the phase 1 dose-expansion study.

Haruru KotaniNorikazu MasudaToshinari YamashitaYoichi NaitoTetsuhiko TairaKenichi InoueMasato TakahashiKan YonemoriShigeyuki ToyoizumiYuko MoriTakashi NagasawaNatsuki HoriHiroji Iwata
Published in: Breast cancer (Tokyo, Japan) (2022)
NCT03343054.
Keyphrases
  • metastatic breast cancer
  • locally advanced
  • squamous cell carcinoma
  • rectal cancer
  • neoadjuvant chemotherapy
  • dna repair
  • radiation therapy
  • clinical trial
  • oxidative stress
  • open label