A randomized controlled trial to compare immunogenicity to cell-based vs. live-attenuated influenza vaccines in children.

Katherine V WilliamsZhu-Nan LiBo ZhaiJohn F AlcornMary Patricia NowalkMin Z LevineSara S KimBrendan FlanneryKrissy Moehling GeffelAmanda Jaber MerrankoMark CollinsMichael SusickKaren S ClarkeRichard K ZimmermanJudith M Martin

Published in: Journal of the Pediatric Infectious Diseases Society (2023)

Age and prior season vaccination may play a role in the immune response in children and young adults to ccIIV4 and LAIV4. While immunoglobulin isotypes provide high level antigen-specific information, HAI titers alone can provide a meaningful representation of day 28 post vaccination response.

Keyphrases

young adults
immune response
single cell
stem cells
cell therapy
social media
inflammatory response