Mycoplasma hyorhinis reduces sensitivity of human lung carcinoma cells to Nutlin-3 and promotes their malignant phenotype.
Uljana A BoyarskikhAlexandra S ShadrinaMariya A SmetaninaYakov A TsepilovIgor P OscorbinVadim V KozlovAlexander E KelMaxim L FilipenkoPublished in: Journal of cancer research and clinical oncology (2018)
Our results provide evidence that mycoplasma infection is an important factor modulating the effect of MDM2 inhibitors on cancer cells and is able to induce EMT-related changes.