Reassignment of NMR spectroscopic data of oleana-9(11),12-diene-3 β -ol isolated from Jeffreycia zeylanica and its wound healing potential in terms of cell migration and proangiogenic activity 1 .

Jeffreycia zeylanica (Asteraceae), a plant endemic to Sri Lanka, is used for the treatment of wounds. The scratch wound assay (SWA) guided fractionation of hexanes extract of J. zeylanica led to the isolation of oleana-9(11),12-diene-3 β -ol ( 1 ) which showed enhanced cell migration in SWA and significant proangiogenic response in chorioallantoic membrane (CAM) assay. Since the reported 1 H NMR assignments of 1 were incomplete, and some 13 C NMR assignments were inconsistent with our observations, reassignment of NMR spectroscopic data of 1 was carried out. Herein we report unambiguous assignment of NMR data of 1 based on 1D and 2D NMR spectra. This is the first report of 1 in J. zeylanica .