Decellularized Wharton Jelly Implants Do Not Trigger Collagen and Cartilaginous Tissue Production in Tracheal Injury in Rabbits.
Katia Martins FoltzAloysio Enck NetoJulio César FranciscoRossana Baggio SimeoniAnna Flávia Ribeiro Dos Santos MiggiolaroThatyanne Gradowski do NascimentoBassam Felipe MogharbelKatherine Athayde Teixeira de CarvalhoJosé Rocha Faria NetoAnna Flávia Ribeiro Dos Santos MiggiolaroLuiz César Guarita-SouzaPublished in: Life (Basel, Switzerland) (2022)
The scaffold appears to fit as a heterologous implant and did not trigger reactions such as rejection or extrusion of the material into the recipient. However, these results suggested that although the WJ matrix presents several characteristics as a biomaterial for tissue regeneration, it did not display histopathological benefits in trachea tissue regeneration.