Epigenetic and Epitranscriptomic Factors Make a Mark on Hematopoietic Stem Cell Development.

Dionna M KasperStefania Nicoli

Published in: Current stem cell reports (2018)

Epigenetic and epitranscriptomic regulation are key mechanisms for reshaping global EC gene expression patterns to those that support HSC production. Future studies that capture modification dynamics should bring us closer to a complete understanding of how HSCs transition from hemogenic endothelium at the molecular level.

Keyphrases

gene expression
hematopoietic stem cell
dna methylation
nitric oxide
current status
case control
single molecule