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Platelet-activating factor acetylhydrolase is a biomarker of severe anaphylaxis in children.

Julia E M UptonJennifer A HoangMatilde Leon-PonteYaron FinkelsteinYue Jennifer DuKhosrow AdeliThomas EiweggerEyal GrunebaumPeter Vadas
Published in: Allergy (2022)
Decreased serum PAF-AH activity is a biomarker of severe anaphylaxis. Levels of this enzyme do not change from basal levels during acute anaphylaxis. Our results show that PAF-AH is a biomarker of anaphylaxis severity in children. This key regulatory enzyme may modulate susceptibility to severe anaphylaxis.
Keyphrases
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