COVID-19 in the nervous system: physiopathology and neurological manifestations.

Valder Cavalcante Maia Mendonça Filho Amanda Gomes de Oliveira Isabelle de Fátima Vieira Camelo Maia Ananda Carolina Moraes de Falcone Beatriz Gioppo Betini Lucas Bruno Rezende Fernando Henrique Magri Alves

Published in: Arquivos de neuro-psiquiatria (2023)

Coronavirus-2 presents neurotropism, and it can reach the CNS by hematogenous dissemination and by direct infection of the nerve endings. It causes brain injuries through several mechanisms, such as cytokine storm, microglial activation, and an increase in thrombotic factors.

Keyphrases

sars cov
coronavirus disease
cerebral ischemia
respiratory syndrome coronavirus
blood brain barrier
resting state
white matter
inflammatory response
lipopolysaccharide induced
lps induced
neuropathic pain
peripheral nerve
functional connectivity
subarachnoid hemorrhage
multiple sclerosis