Zinc deficiency induces hypertension by paradoxically amplifying salt sensitivity under high salt intake in mice.

Marie YamamotoTomoaki TakataHinako HanadaSosuke TaniguchiShintaro HamadaYukari MaeTakuji IyamaTsutomu KandaHajime Isomoto

Published in: Clinical and experimental nephrology (2024)

The combination of zinc deficiency and high salt causes hypertension. Zinc is associated with salt-sensitivity, potentially through NHE3 and NCC regulation.

Keyphrases

blood pressure
oxide nanoparticles
replacement therapy
metabolic syndrome
type diabetes
body mass index
high fat diet induced
skeletal muscle
weight gain
arterial hypertension