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Preparation of Pueraria lobata Root-Derived Exosome-Like Nanovesicles and Evaluation of Their Effects on Mitigating Alcoholic Intoxication and Promoting Alcohol Metabolism in Mice.

Wenjin ZhangQiang SongXiaofei BiWei CuiChengmei FangJianya GaoJinan LiXiang WangKai QuXian QinXuan AnCheng ZhangXianxiang ZhangFang YanGuicheng Wu
Published in: International journal of nanomedicine (2024)
P-ELNs exhibit distinct exosomal characteristics and effectively alleviate alcoholic intoxication, improve alcohol metabolism, suppress ferroptosis, and protect the liver from alcoholic injury. Consequently, P-ELNs hold promise as a therapeutic agent for detoxification, sobriety promotion, and prevention of alcoholic liver injury.
Keyphrases
  • liver injury
  • drug induced
  • cell death
  • type diabetes
  • adipose tissue
  • high resolution
  • skeletal muscle
  • high fat diet induced
  • mass spectrometry
  • solid phase extraction