Cross-platform analysis reveals cellular and molecular landscape of glioblastoma invasion.

Ann T ChenYang XiaoXiangjun TangMehdi BaqriXingchun GaoMelanie ReschkeWendy C SheuGretchen LongYu ZhouGang DengShenqi ZhangYanxiang DengZhiliang BaiDongjoo KimAnita HuttnerRussell KunesMurat GünelJennifer MoliternoW Mark SaltzmanRong FanJiangbing Zhou

Published in: Neuro-oncology (2022)

Collectively, our analysis identifies differentially expressed features between invasive and nodular GBM, and describes a novel relationship between CRYAB and CD44 that contributes to tumor invasiveness, establishing a cellular and molecular landscape of GBM invasion.

Keyphrases

cell migration
single cell
genome wide
high throughput
single molecule