Lower plasma melatonin levels in non-hypoxic premature newborns associated with neonatal pain.

Cristina Sánchez-Borja Delia Cristóbal CañadasMaría Isabel Rodríguez-LucenillaAntonio Muñoz-Hoyos Ahmed AgilMaría Ángeles Vázquez-LópezTesifón Parron-Carreño Bruno José Nievas-Soriano Antonio Bonillo-Perales Juan Carlos Bonillo-Perales

Published in: European journal of pediatrics (2024)

• Non-hypoxic preterm infants with moderate to severe pain (PIPP>5) have lower levels of melatonin. • Administration of caffeine and treatment with parenteral nutrition do not modify melatonin levels in non-hypoxic preterm infants.

Keyphrases

preterm infants
low birth weight
chronic pain
pain management
neuropathic pain
high intensity
early onset