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Determination of distinctive hypomethylated genes in African American colorectal neoplastic lesions.

Hassan AshktorabKareem WashingtonShatha ZarnogiAfnan ShakooriSudhir VarmaEdward LeeBabak ShokraniAdeyinka LaiyemoAfnan M Shakoori
Published in: Therapeutic advances in gastroenterology (2020)
This work provides insight into the role of hypomethylation in colon carcinogenesis in African Americans. The identified targets affected many important pathways, as demonstrated through IPA. These targets might serve as biomarkers for early diagnosis and potential targets for therapy.
Keyphrases
  • african american
  • genome wide
  • stem cells
  • dna methylation
  • high resolution
  • cell therapy
  • genome wide identification
  • bioinformatics analysis