Mediterranean Diet: The Beneficial Effects of Lycopene in Non-Alcoholic Fatty Liver Disease.
Ludovico Montebianco AbenavoliAnna Caterina ProcopioMaria Rosaria ParavatiGiosuè CostaNataša MilićStefano AlcaroFrancesco LuzzaPublished in: Journal of clinical medicine (2022)
Non-alcoholic fatty liver disease (NAFLD) presents the most common chronic liver disease globally; it is estimated that 25.24% of the world's population has NAFLD. NAFLD is a multi-factorial disease whose development involves various processes, such as insulin resistance, lipotoxicity, inflammation, cytokine imbalance, the activation of innate immunity, microbiota and environmental and genetic factors. Numerous clinical studies have shown that the Mediterranean diet produces beneficial effects in NAFLD patients. The aim of this review is to summarize the beneficial effects of lycopene, a soluble pigment found in fruit and vegetables, in NAFLD.
Keyphrases
- insulin resistance
- end stage renal disease
- ejection fraction
- newly diagnosed
- oxidative stress
- chronic kidney disease
- type diabetes
- prognostic factors
- metabolic syndrome
- adipose tissue
- human health
- skeletal muscle
- high fat diet
- risk assessment
- gene expression
- liver fibrosis
- patient reported outcomes
- climate change
- weight loss
- high fat diet induced
- glycemic control