Low interobserver agreement among subspecialised breast pathologists in evaluating HER2-low breast cancer.

Gulisa TurashviliYuan GaoDi Andy AiAbdulwahab M EwazSandra Gjorgova GjeorgjievskiQun WangThi T A NguyenChao ZhangXiaoxian Li

Published in: Journal of clinical pathology (2023)

Subspecialised breast pathologists have suboptimal agreement for immunohistochemical evaluation of HLBC using the modified Ki-67 methodology. An urgent need remains for a new assay/algorithm to reliably evaluate HLBC.

Keyphrases

machine learning
deep learning
high throughput
neoadjuvant chemotherapy
radiation therapy