The role of intracellular trafficking of CdSe/ZnS QDs on their consequent toxicity profile.

Bella B ManshianThomas F MartensKarsten KantnerKevin BraeckmansStefaan C De SmedtJo DemeesterGareth J S JenkinsWolfgang J ParakBeatriz PelazShareen H DoakUwe HimmelreichStefaan J Soenen

Published in: Journal of nanobiotechnology (2017)

Together, these data reveal that although cellular QD levels were similar after 24 h, differences in the nature and extent of their cellular trafficking resulted in differences in consequent gene alterations and toxicological effects.

Keyphrases

quantum dots
genome wide
oxidative stress
electronic health record
copy number
single cell
big data
oxide nanoparticles
gene expression
machine learning