An increase in myocardial 18-fluorodeoxyglucose uptake is associated with left ventricular ejection fraction decline in Hodgkin lymphoma patients treated with anthracycline.
Matteo SarocchiMatteo BaucknehtEleonora ArboscelloSelene CapitanioCecilia MariniSilvia MorbelliMaurizio MiglinoAngela Giovanna CongiuGiorgio GhigliottiManrico BalbiClaudio BrunelliGianmario SambucetiPietro AmeriPaolo SpallarossaPublished in: Journal of translational medicine (2018)
DOX-containing chemotherapy causes an increase in cardiac 18FDG uptake, which is associated with a decline in LVEF. Future studies are warranted to understand the molecular basis and the potential clinical implications of this observation.
Keyphrases
- left ventricular
- ejection fraction
- hodgkin lymphoma
- aortic stenosis
- positron emission tomography
- pet ct
- computed tomography
- hypertrophic cardiomyopathy
- acute myocardial infarction
- heart failure
- cardiac resynchronization therapy
- mitral valve
- left atrial
- pet imaging
- locally advanced
- transcatheter aortic valve replacement
- current status
- squamous cell carcinoma
- radiation therapy
- percutaneous coronary intervention
- rectal cancer