A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides.

Mihaela PericDijana PešićSulejman AlihodžićAndrea FajdetićEsperanza HerrerosFrancisco Javier GamoIñigo Angulo-BarturenMaría Belén Jiménez-DíazSantiago Ferrer-BazagaMaría S MartínezDomingo Gargallo-ViolaAmanda MathisAlbane KesslerMihailo BanjanacJasna PadovanVlatka Bencetić MihaljevićVesna Munic KosMirjana BukvićVesna Eraković HaberRadan Spaventi

Published in: British journal of pharmacology (2020)

The hybrid derivatives described here represent excellent antimalarial drug candidates with the potential for clinical use in malaria therapy.

Keyphrases

plasmodium falciparum
molecular docking
human health
adverse drug
bone marrow
drug induced
mesenchymal stem cells
molecular dynamics simulations