Immunosuppressive Phenotype of Esophagus Tumors Stroma.

Olga V KovalevaMadina A RashidovaDaria V SamoilovaPolina A PodlesnayaValeria V MochalnikovaAlexei Gratchev

Published in: Analytical cellular pathology (Amsterdam) (2020)

Large amounts of CD163+ macrophages and FOXP3+ Т cells appear to be markers of good prognosis of ESCC. The number of PU.1+ macrophages strongly correlates with the number of CD68+ macrophages; therefore, usage of PU.1 as a potential macrophage marker can be recommended for esophageal tumors.

Keyphrases

induced apoptosis
regulatory t cells
cell cycle arrest
adipose tissue
nk cells
cell death
endoplasmic reticulum stress