Prevalence of Mycobacterium tuberculosis infection as measured by the QuantiFERON-TB Gold assay and ESAT-6 free IGRA among adolescents in Mwanza, Tanzania.

Kidola JeremiahEric LyimoChristian RitzGeorge PrayGodKathryn Tucker RutkowskiKaren Smith KorsholmMorten RuhwaldDereck TaitHarleen M S GrewalDaniel Faurholt-Jepsen

Published in: PloS one (2021)

The prevalence of LTBI and the associated ARTI and force of infection among adolescents is high and increases with age in Mwanza Region. There was a high concordance between the QFT-GIT and the novel ESAT-6 free IGRA assays. These findings suggest Mwanza is a promising area to conduct novel TB vaccine research prevention of infection (POI) studies targeting adolescents.

Keyphrases

mycobacterium tuberculosis
risk factors
high throughput
physical activity
pulmonary tuberculosis
cancer therapy
case control