Type 1 Angiotensin Receptors on CD11c-Expressing Cells Protect Against Hypertension by Regulating Dendritic Cell-Mediated T Cell Activation.
Xiaohan LuJiandong ZhangYi WenJiafa RenRobert GriffithsNathan P RudemillerShintaro IdeTomokazu SoumaSteven D CrowleyPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
Following activation of the renin angiotensin system, AT1aR stimulation on DCs suppresses renal DC maturation and T cell activation with consequent protection from sodium retention and blood pressure elevation.