Prognosis of spontaneous pneumomediastinum occurring in dermatomyositis or polymyositis patients with interstitial lung disease according to antimelanoma differentiation-associated gene 5 antibody status: a retrospective cohort study.
Kazuya AbeShunsuke FurutaYoshihisa KobayashiTakao SugiyamaShin-Ichiro KagamiDaiki NakagomiTaro IwamotoKei IkedaHiroshi NakajimaPublished in: RMD open (2023)
SPNM occurred more frequently in anti-MDA5 antibody-positive than in anti-MDA5 antibody-negative myositis patients. SPNM occurrence was associated with higher mortality risk, especially in anti-MDA5 antibody-positive patients.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- breast cancer cells
- prognostic factors
- idiopathic pulmonary fibrosis
- gene expression
- risk assessment
- dna methylation
- patient reported outcomes
- cell proliferation
- cell death
- transcription factor
- signaling pathway
- cell cycle arrest