Molecularly Guided Drug Repurposing for Cholangiocarcinoma: An Integrative Bioinformatic Approach.

Simran Venkatraman Brinda BalasubramanianPisut PongchaikulRutaiwan Tohtong Somchai Chutipongtanate

Published in: Genes (2022)

This study proposes the use of the immune-oncogenic gene signature to identify high-risk CCA patients. Future preclinical and clinical studies are required to elucidate the therapeutic efficacy of the molecularly guided drugs as the adjunct therapy, aiming to improve the survival outcome.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
genome wide
stem cells
gene expression
cell therapy
dna methylation
genome wide identification