Predicting response after infliximab salvage in acute severe ulcerative colitis.

Matthew C ChoyDean SeahAlexandra GorelikYoon-Kyo AnCheng-Yu ChenFinlay A MacraeMiles P SparrowWilliam R ConnellGregory T MooreGraham Radford-SmithDaniel R Van LangenbergPeter De Cruz

Published in: Journal of gastroenterology and hepatology (2018)

The baseline Mayo Endoscopic Score and the CRP/albumin ratio following infliximab salvage are significant predictors of treatment response for ASUC and identify patients at high risk of colectomy. Whether this risk can be mitigated using infliximab dose intensification requires prospective evaluation before the CRP/albumin ratio can be integrated into ASUC management algorithms.

Keyphrases

ulcerative colitis
machine learning
liver failure
drug induced
respiratory failure
deep learning
early onset
intensive care unit
aortic dissection
mechanical ventilation
acute respiratory distress syndrome
endoscopic submucosal dissection