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Surveillance for peri-elimination trachoma recrudescence: Exploratory studies in Ghana.

Laura G SenyonjoJames AddyDiana L MartinDavid AgyemangDorothy Yeboah-ManuSarah GwynBenjamin MarfoAdwoa Asante-PokuAgatha AboeErnest MensahAnthony W SolomonRobin L Bailey
Published in: PLoS neglected tropical diseases (2021)
There is evidence of heterogeneity in Ct transmission dynamics in northern Ghana, even 10 years after wide-scale MDA has stopped. There is added value in monitoring Ct infection and anti-Ct antibodies, using these indicators to interrogate past or present surveillance strategies. This can result in a deeper understanding of transmission dynamics and inform new post-validation surveillance strategies. Opportunities should be explored for integrating PCR and serological-based markers into surveys conducted in trachoma elimination settings.
Keyphrases
  • image quality
  • dual energy
  • public health
  • computed tomography
  • contrast enhanced
  • positron emission tomography
  • single cell
  • cell proliferation
  • signaling pathway