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LncRNA MIR4435-2HG mediates cisplatin resistance in HCT116 cells by regulating Nrf2 and HO-1.

Ping LuoShugui WuKaibao JiXia YuanHongmi LiJinping ChenYunfei TianYang QiuXiaoming Zhong
Published in: PloS one (2020)
Our findings demonstrate that the lncRNA MIR4435-2HG is a main factor driving the cisplatin resistance of HCT116 cells.
Keyphrases
  • cell cycle arrest
  • long non coding rna
  • induced apoptosis
  • long noncoding rna
  • pi k akt
  • cell death
  • oxidative stress
  • endoplasmic reticulum stress
  • signaling pathway
  • fluorescent probe
  • living cells
  • single molecule