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Genetic characteristics of non-familial epilepsy.

Kyung Wook KangWonkuk KimYong-Won ChoSang Kun LeeKi-Young JungWonchul ShinDong Wook KimWon-Joo KimHyang Woon LeeWoojun KimKeun Tae KimSo-Hyun LeeSeok-Yong ChoiMyeong-Kyu Kim
Published in: PeerJ (2019)
We revealed a fraction of possible causal genetic variants of non-familial epilepsies in which genetic testing is usually overlooked. In this study, we highlight the importance of earlier identification of the genetic etiology of non-familial epilepsies, which leads us to the best treatment options in terms of precision medicine and to future neurobiological research for novel drug development. This should be considered a justification for physicians determining the hidden genetics of non-familial epilepsies that last until or start in adulthood.
Keyphrases
  • early onset
  • genome wide
  • primary care
  • copy number
  • depressive symptoms
  • gene expression