Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy.
Songfa ZhangChuan YanDavid G MillarQiqi YangJames M HeatherAdam LangenbucherLaura T MortonSean SepulvedaEric AlpertLauren R WheltonDominique T ZarrellaMei GuoEleanor MinogueMichael S LawrenceBo R RuedaDavid R SpriggsWeiguo LuDavid M LangenauMark CobboldPublished in: Cancer research (2022)
This study develops a high-throughput preclinical platform to identify patient-specific antibody-peptide epitope conjugates that target cancer cells and demonstrates the potential of this immunotherapy approach for treating ovarian carcinoma.