Pharmacovigilance of nephrotoxic drugs in neonates: the Pottel method for acute kidney injury detection in ELBW neonates.

Mathilde Dumoulin Hans Pottel Djalila Mekahli Annouschka Laenen Anne Smits Karel Allegaert

Published in: Pediatric nephrology (Berlin, Germany) (2024)

As rescaled Scr biomarker, the Pottel method showed a clear association with ibuprofen-exposed ELBW neonates, suggesting its applicability as a pragmatic bedside alternative tool to assess nephrotoxicity.

Keyphrases

acute kidney injury
low birth weight
drug induced
cardiac surgery
adverse drug
loop mediated isothermal amplification
real time pcr
label free
postoperative pain
double blind