Safety of Intravitreal Gene Therapy for Treatment of Subjects with Leber Hereditary Optic Neuropathy due to Mutations in the Mitochondrial ND4 Gene: The REVEAL Study.

Catherine Vignal-ClermontJean-François GirmensIsabelle AudoSaddek Mohand SaidMarie-Hélène ErreraLise PlaineDenis O'ShaughnessyNancy J NewmanJosé-Alain Sahel

Published in: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy (2021)

EUDRACT N° 2013-001405-90.

Keyphrases

gene therapy
genome wide
oxidative stress
vascular endothelial growth factor
copy number
diabetic retinopathy
transcription factor
replacement therapy
smoking cessation
genome wide analysis