Topological Analysis and Structural Determination of Three-dimensional Covalent Organic Frameworks.

Three-dimensional covalent organic frameworks (3D COFs) constitute a new type of crystalline materials that consist of a range of porous structures with numerous applications in the fields of adsorption, separation, and catalysis. However, because of the complexity of the three-periodic net structure, it would be desirable to develop a thorough structural comprehension, along with a means to precisely determine the actual structure. Indeed, such advancements would considerably contribute to the rational design and application of 3D COFs. In this review, we introduce and categorize the reported topologies of 3D COFs according to the configurations of their building blocks, and provide a comprehensive overview of diffraction-based structural determination methods. The current challenges and future prospects for these materials will also be discussed. This article is protected by copyright. All rights reserved.