Short- and long-term safety of discontinuing chronic opioid therapy among older adults with Alzheimer's disease and related dementia.

Yu-Jung Jenny WeiAlmut G WintersteinSiegfried SchmidtRoger B FillingimStephan SchmidtMichael J DanielsSteven T DeKosky

Published in: Age and ageing (2024)

The rates of adverse outcomes were higher in the first quarter but lower or non-differential at 1-year and 2-year follow-ups between COT discontinuers versus continuers among older residents with ADRD.

Keyphrases

mild cognitive impairment
cognitive decline
chronic pain
pain management
cognitive impairment
drug induced