Performance evaluation of the UMIC® Cefiderocol to determine MIC in Gram-negative bacteria.

Laurent DortetClaudia NiccolaiNiels PfennigwerthStefanie FrischCamille GonzalezAlberto AntonelliTommaso GianiRobert HoeningsSoeren GatermannGian Maria RossoliniThierry Naas

Published in: The Journal of antimicrobial chemotherapy (2023)

UMIC® Cefiderocol is a valid method for the determination of cefiderocol MICs even if higher than expected discrepancies were observed with NDM-producing Enterobacterales, which presented in most cases MIC values close to the breakpoint.

Keyphrases

gram negative
multidrug resistant
klebsiella pneumoniae
solid phase extraction
molecularly imprinted
escherichia coli
high resolution
tandem mass spectrometry