Use of multi-trait and random regression models to identify genetic variation in tolerance to porcine reproductive and respiratory syndrome virus.

Graham LoughHamed RashidiIlias KyriazakisJack C M DekkersAndrew HessMelanie HessNader DeebAntti KauseJoan K LunneyRaymond R R RowlandHan A MulderAndrea Doeschl-Wilson

Published in: Genetics, selection, evolution : GSE (2017)

Evidence for genetic variation in tolerance of pigs to PRRS was weak when based on data from infected piglets only. However, simulations indicated that genetic variance in tolerance may exist and could be detected if comparable data on uninfected relatives were available. In conclusion, of the two defense strategies, genetics of tolerance is more difficult to elucidate than genetics of resistance.

Keyphrases

electronic health record
genome wide
big data
hiv infected
machine learning
dna methylation
neural network
innate immune