Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation.
Maria Sparreman MikusJohan KolmertLars I AnderssonJörgen ÖstlingRichard G KnowlesCristina GómezMagnus EricssonJohn-Olof ThörngrenPayam Emami KhoonsariBarbro DahlénMaciej KupczykBertrand De MeulderCharles AuffrayPer S BakkeBianca BegheElisabeth H BelMassimo CarusoPascal ChanezBo ChawesStephen J FowlerMina GagaThomas GeiserMark GjomarkajIldikó HorváthPeter H HowarthSebastian L JohnstonGuy F JoosNorbert KrugPaolo MontuschiJacek MusialEwa Niżankowska-MogilnickaHenric K OlssonAlberto PapiKlaus F RabeThomas SandströmDominick E ShawNikolaos M SiafakasMathias UhlenJohn H RileyStewart BatesRoelinde J M MiddelveldCraig E WheelockKian Fan ChungIssssswan M AdcockPeter J SterkRatko DjukanovicPeter NilssonSven-Erik DahlénAnna Jamesnull nullnull nullPublished in: The European respiratory journal (2021)
The plasma proteomic panel revealed previously unexplored yet potentially useful Type-2-independent biomarkers, and validated several proteins with established involvement in the pathophysiology of severe asthma.
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