Effects of tolcapone and bromocriptine on cognitive stability and flexibility.
Ian G M CameronDeanna L WallaceAhmad Al-ZughoulAndrew S KayserMark D'EspositoPublished in: Psychopharmacology (2018)
Optimal behavior was based on obeying the environmental stimuli, and we found reduced efficiency with greater PFC dopamine tone. We suggest that greater PFC dopamine interfered with the ability to flexibly follow the environment.