Protective Role of Myelocytic Nitric Oxide Synthases against Hypoxic Pulmonary Hypertension in Mice.

Takaaki OgoshiMasato TsutsuiTakashi KidoMayuko SakanashiKeisuke NaitoKeishi OdaHiroshi IshimotoSohsuke YamadaKe-Yong WangYumiko ToyohiraHiroto IzumiHiroaki MasuzakiHiroaki ShimokawaNobuyuki YanagiharaKazuhiro YateraHiroshi Mukae

Published in: American journal of respiratory and critical care medicine (2019)

These results demonstrate that myelocytic n/i/eNOSs play an important protective role in the pathogenesis of PH.

Keyphrases

pulmonary hypertension
nitric oxide
pulmonary artery
high fat diet induced
pulmonary arterial hypertension
nitric oxide synthase
hydrogen peroxide
type diabetes
metabolic syndrome
insulin resistance
coronary artery
skeletal muscle