Login / Signup

A Green Light to Switch on Genes: Revisiting Trithorax on Plants.

Diego Ornelas-AyalaCarlos Cortés-QuiñonesJosé Olvera-HerreraBerenice García-PonceAdriana Garay-ArroyoElena R Álvarez-BuyllaMaria de la Paz Sanchez
Published in: Plants (Basel, Switzerland) (2022)
The Trithorax Group (TrxG) is a highly conserved multiprotein activation complex, initially defined by its antagonistic activity with the PcG repressor complex. TrxG regulates transcriptional activation by the deposition of H3K4me3 and H3K36me3 marks. According to the function and evolutionary origin, several proteins have been defined as TrxG in plants; nevertheless, little is known about their interactions and if they can form TrxG complexes. Recent evidence suggests the existence of new TrxG components as well as new interactions of some TrxG complexes that may be acting in specific tissues in plants. In this review, we bring together the latest research on the topic, exploring the interactions and roles of TrxG proteins at different developmental stages, required for the fine-tuned transcriptional activation of genes at the right time and place. Shedding light on the molecular mechanism by which TrxG is recruited and regulates transcription.
Keyphrases
  • transcription factor
  • gene expression
  • genome wide
  • air pollution
  • genome wide identification
  • dna methylation