Dorsal raphe serotonergic neurons promote arousal from isoflurane anesthesia.
Ao LiRui LiPengrong OuyangHuihui LiSa WangXinxin ZhangDan WangMingzi RanGuangchao ZhaoQianzi YangZhenghua ZhuHailong DongHaopeng ZhangPublished in: CNS neuroscience & therapeutics (2021)
Our results demonstrate that 5-HT neurons in the DRN play a regulative role of general anesthesia, and activation of serotonergic neurons could facilitate emergence from general anesthesia partly through 5-HT 1A and 2C receptors.
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