The junctional adhesion molecule-like protein (JAML) is important for the inflammatory response during contact hypersensitivity.
Veronika MrazRebecca K D LohmannMandy MenzelAlana HawkesHelen VaherAnders Boutrup FunchMia Hamilton JeeAnne-Sofie Østergaard GadsbøllJulie Friis WeberKelvin YeungNiels OdumAnders WoetmannDianne B McKayDeborah A WitherdenCarsten GeislerCharlotte Menné BonefeldPublished in: Contact dermatitis (2023)
Our study is the first to show a central role of JAML in CHS and reveals a potential new target for the treatment of ACD in humans.