Bridging the Gap in Cancer-Related Stroke Management: Update on Therapeutic and Preventive Approaches.
Ming-Yee SunSonu Menachem Maimonides BhaskarPublished in: International journal of molecular sciences (2023)
The underlying aetiopathophysiology of cancer-related strokes and thromboembolisms differs from that of noncancer-related strokes, which makes treating cancer-related strokes and thromboembolisms a distinct clinical challenge. This necessitates the development of novel, individualised diagnostic and treatment strategies. However, limited guidelines are available for the management of cancer-related strokes and the prevention of acute strokes or other thromboembolic events in this patient population. In this article, we present an updated overview of the therapeutic and preventive strategies for strokes in cancer settings. These strategies include acute reperfusion therapy, anticoagulant therapy, antiplatelet therapy, and lifestyle management options. We also outline comprehensive pathways and highlight gaps in the evidence-based clinical management of cancer-related strokes or thromboembolisms. Additionally, future recommendations for the management of strokes in cancer patients are provided.
Keyphrases
- antiplatelet therapy
- atrial fibrillation
- cardiovascular disease
- acute coronary syndrome
- drug induced
- clinical practice
- physical activity
- stem cells
- venous thromboembolism
- case report
- bone marrow
- heart failure
- acute myocardial infarction
- intensive care unit
- extracorporeal membrane oxygenation
- weight loss
- acute ischemic stroke
- smoking cessation
- replacement therapy