[Challenge abstinence-a case report and overview on therapy of alcohol dependence during pregnancy].

The potentially deleterious and teratogen effects of alcohol consumption during pregnancy are an important medical as well as socio-economic topic. Maintaining the necessary strict abstinence is especially challenging for pregnant women diagnosed with alcohol dependence. Due to limited data, optimal pharmacological treatment is seldom possible. Importantly, all substances currently approved for relapse prevention are contraindicated during pregnancy. Limited data concerning the off-label-use of Ondansetron (5-HT3 receptor antagonist) as relapse prevention during pregnancy exists. In the portrayed case-report, a pregnant patient received psychopharmacological treatment with Sertraline, Quetiapine and Ondansetron. Under this established pharmacological therapy, the patient achieved abstinence for the remainder of the pregnancy.