Chronic stress induces hypersensitivity of murine gastric vagal afferents.

Hui LiFemke T A Buisman-PijlmanMaria Nunez-SalcesStewart ChristieClaudine L FrisbyAntonio InserraGeorge HatzinikolasMartin D LewisStamatiki KritasMa-Li WongAmanda J Page

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)

In conclusion, chronic stress enhances GVA mechanosensitivity, which may contribute to the gastric hypersensitivity in FD. In addition, the modulatory effect of leptin on GVA signaling is lost after chronic stress exposure.

Keyphrases

drug induced