Advances and opportunities in nanoimaging agents for the diagnosis of inflammatory lung diseases.
Hema Brindha MasanamGovindaraj PerumalSaravanan KrishnanSachin Kumar SinghNiraj Kumar JhaDinesh Kumar ChellappanKamal DuaPiyush Kumar GuptaAshwin Kumar NarasimhanPublished in: Nanomedicine (London, England) (2023)
The development of rapid, noninvasive diagnostics to detect lung diseases is a great need after the COVID-2019 outbreak. The nanotechnology-based approach has improved imaging and facilitates the early diagnosis of inflammatory lung diseases. The multifunctional properties of nanoprobes enable better spatial-temporal resolution and a high signal-to-noise ratio in imaging. Targeted nanoimaging agents have been used to bind specific tissues in inflammatory lungs for early-stage diagnosis. However, nanobased imaging approaches for inflammatory lung diseases are still in their infancy. This review provides a solution-focused approach to exploring medical imaging technologies and nanoprobes for the detection of inflammatory lung diseases. Prospects for the development of contrast agents for lung disease detection are also discussed.