Does cystic fibrosis constitute an advantage in COVID-19 infection?
Valentino BezzerriFrancesca LuccaSonia VolpiMarco CipolliPublished in: Italian journal of pediatrics (2020)
The Veneto region is one of the most affected Italian regions by COVID-19. Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), may constitute a risk factor in COVID-19. Moreover, respiratory viruses were generally associated with severe pulmonary impairment in cystic fibrosis (CF). We would have therefore expected numerous cases of severe COVID-19 among the CF population. Surprisingly, we found that CF patients were significantly protected against infection by SARS-CoV-2. We discussed this aspect formulating some reasonable theories.
Keyphrases
- cystic fibrosis
- sars cov
- lung function
- chronic obstructive pulmonary disease
- coronavirus disease
- pseudomonas aeruginosa
- respiratory syndrome coronavirus
- end stage renal disease
- risk factors
- ejection fraction
- chronic kidney disease
- early onset
- newly diagnosed
- pulmonary hypertension
- patient reported outcomes
- air pollution
- respiratory tract