Survival outcomes and toxicity profiles among patients with nonmetastatic nasopharyngeal carcinoma treated with intensity-modulated radiotherapy (IMRT) versus IMRT + carbon-ion radiotherapy: A propensity score-matched analysis.
Yujiao LiXiyin GuanXing XingChaosu HuPublished in: Head & neck (2024)
In this study, IMRT + CIRT was associated with significantly reduced acute toxicity burden compared with full course of IMRT, with excellent survival outcomes. Patients with persistent disease after treatment and treated with nodal boost had a worse outcome. More accurate assessments of IMRT + CIRT to primary nonmetastatic NPC patients will be imperative.
Keyphrases
- newly diagnosed
- end stage renal disease
- early stage
- chronic kidney disease
- ejection fraction
- radiation therapy
- oxidative stress
- liver failure
- radiation induced
- peritoneal dialysis
- lymph node
- prognostic factors
- high resolution
- squamous cell carcinoma
- neoadjuvant chemotherapy
- hepatitis b virus
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome